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KYPROLIS, DARZALEX Combo Approved for Multiple Myeloma

The study's primary endpoint resulted in a 37% reduction in the risk of disease progression or death.

By: Contract Pharma

Contract Pharma Staff

Amgen received approval from the FDA for the expansion of KYPROLIS (carfilzomib) to include its use in combination with Janssen’s DARZALEX (daratumumab) plus dexamethasone (DKd) in two dosing regimens — once weekly and twice weekly — for the treatment of patients with relapsed or refractory multiple myeloma who have received one to three previous lines of therapy. “This expanded approval for KYPROLIS demonstrates a leap forward in the treatment paradigm for this complex disease b...

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